Substrate Reduction Therapy (SRT) Innovations in the US Fabry Disease Market
Developing oral substrate reduction therapies (SRT) to inhibit upstream glycosphingolipid biosynthesis is expanding non-enzyme treatment options within the US Fabry Disease Market. Substrate reduction therapies utilize small-molecule inhibitors to target glucosylceramide synthase, the key enzyme responsible for initiating glycosphingolipid synthesis. Decreasing the rate of cellular...
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